essential hypertension — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T6595	Moexipril hydrochloride	Moexipril HCl,RS-10085,SPM 925,CI-925	Apoptosis , RAAS
	Moexipril hydrochloride (Moexipril HCl) is a potent orally active nonsulfhydrylangiotensin converting enzyme (ACE)inhibitor, used for the treatment of hypertension and congestive heart failure.		Apoptosis , RAAS
T2621	Rostafuroxin	PST 2238	ATPase , RSV
	Rostafuroxin (PST 2238) has been used in trials studying the treatment of Essential Hypertension.		ATPase , RSV
T17056	Tetrahydrobiopterin	Sapropterin,BH4,(Rac)-Sapropterin	NOS , Endogenous Metabolite
	Tetrahydrobiopterin (BH4) is a cofactor for aromatic amino acid hydroxylases and an essential cofactor for nitric oxide synthase (NOS), which is used in the study of endothelial dysfunction such as hypertension, hypercho...		NOS , Endogenous Metabolite
T6219	Azilsartan Medoxomil	TAK-491	RAAS
	Azilsartan Medoxomil (TAK-491) is an orally administered angiotensin II receptor type 1 antagonist with IC50 of 0.62 nM, which used in the treatment of adults with essential hypertension.		RAAS
T27119L	(Rac)-Daglutril	SLV 306 acetic acid,2-((3S)-3-(1-(2-(ethoxycarbonyl)-4-phenylbutyl)cyclopentane-1-carboxamido)-2-oxo-2,3,4,5-tetrahydro-1H-benzo[b]azepin-1-yl)acetic acid	Others
	(Rac)-Daglutril (SLV 306 acetic acid) is the racemate form of Daglutril. Daglutril is an orally active, mixed neutral endopeptidase/endothelin converting enzyme inhibitor under development for the treatment of essential ...		Others
T20167	Cilazapril	Ro-34-2848,Ro 34-2848,Cilazapril (anhydrous),Ro34-2848
	Cilazapril is an angiotensin-converting enzyme inhibitor. It has been researched for mild to moderate essential hypertension.
T28324	PD 125967	PD125967,PD-125967
	PD 125967 is a renin inhibitor, which represents a group of pharmaceutical drugs used primarily to treat essential hypertension.
T28323	PD 125754	PD125754,PD-125754
	PD 125754 is a Renin inhibitor, which represents a group of pharmaceutical drugs used primarily to treat essential hypertension.
T70522	FK-906 HCl
	FK-906 HCl is a human renin inhibitor used for the long-term treatment of patients with essential hypertension.
T6340L	Enalaprilat	MK422,MK 422,MK 421 diacid,Enalapril acid,MK-422
	Enalaprilat, the active metabolite of Enalapril, is a effective intravenously administered angiotensin-converting enzyme inhibitor. It is an effective agent for the treatment of essential hypertension and has beneficial ...
T27306	Fasidotril	BP 1137,BP1137,BP-1.137,BP1.137,BP-1137,BP 1.137
	Fasidotril is a NEP/ACE inhibitor. Fasidotril was an effective oral antihypertensive agent during chronic treatment in high-renin renovascular rats, normal-renin SHR, and low-renin DOCA-salt hypertensive rats and in pati...
T78567	Moprolol	(±)-Moprolol	Adrenergic Receptor
	Moprolol ((±)-Moprolol) is a beta-adrenergic receptor antagonist utilized in research pertaining to essential hypertension [1] [2] [3].		Adrenergic Receptor
T33673	Niludipine	Niludipina,BAY-a 7168,Bay a 7168,Niludipinum
	Nirudipine is a double (2-propoxyethyl) analogist of nifedipine and a calcium channel blocker, which is also a safe anti-angina Ca2+ antagonist with a broad range of efficacy for all types of angina. At the same time, Ni...
T35871	Bopindolol (malonate)
	Bopindolol is a non-selective β-adrenergic receptor antagonist. In vivo, bopindolol decreases heart rate and blood pressure and attenuates ischemia-induced myocardial acidosis in dogs. Formulations containing bopindolol ...
T9451	Bopindolol
	Bopindolol is an orally active antagonist of β-adrenoceptors (ARs) with partial agonist activity. Bopindolol is non-selective for β1- and β2-ARs and has low affinity for β3-AR subtype. Bopindolol is a prodrug of pindolol...